Thursday, December 6, 2007

Open Source Genetics?

Here's an interesting premise: Wired Blog has an article on "The Open Organism: Genetic Engineering in the Open Source Era". What would happen if you applied the principles of Open Source Software to genetic engineering?
Modularity in computer science has helped unleash crazy amounts of creativity, and new business models derived from user-generated content. Take Google Maps open-API. Or even HTML itself, which allowed users to create graphically sophisticated pages with no real programming knowledge. By putting the hard stuff into a black box and just letting you access what you need to know, user/producers have been able to focus on creating interesting content quickly and easily. What if, in the next decade, the same group of elite users/coders could do the same thing with corn?
They might be a little too optimistic, in my opinion. The allure of Open Source (or indeed any kind of hacking) is that anyone can do it. You don't need much initial investment, beyond the computer which you likely already have. Install Linux, get a GNU compiler of your choice, fire up the text editor and you're in business.

Genetic engineering is not like that. Or maybe it's exactly like that, but at a far grander scale. Instead of a computer*, you need a lab: You need pipettes, petri dishes, microscopes, solutions, PCR machines, microarrays, maybe even a gene sequencer. These things don't come cheap.

But let's assume for a moment that you have all of that already. Then you'll still need the things every programmer takes for granted, the libraries or APIs containing shortcuts to all the common tasks that you don't want to design from the ground up. As a genetic engineer, you'll need promoters, restriction enzymes and specialised vectors, each different depending on what you started with.

It is always possible that in the future, genetics labs and components will become as ubiquitous as computers and code libraries. I'm sure that when we were putting punch-cards into basement-sized supercomputers, open source software development seemed as far away as open source genetic engineering seems today. But the transition still took thirty years. I don't think we have to worry about it just yet.

*Or rather, in addition to.

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